Lynne Neagle was born in Merthyr Tydfil and was educated at Cyfarthfa High School and Reading University.

Prior to her election to the Senedd in 1999, Lynne held a number of posts within the voluntary sector in Wales, working for organisations such as Shelter Cymru, Mind and the CAB. She was Carers Development Officer with Voluntary Action Cardiff and also worked as a researcher for Glenys Kinnock MEP.

Lynne was appointed Deputy Minister for Mental Health and Wellbeing on 13 May 2021.